Since the complicated and changeable condition, many companies are likely to suffer heavy loss for their delayed reaction and poor adaptability. Take BP for example. The event of the Gulf of Mexico oil spill would warn us that efficient reforms must be taken in terms of the organizational design and other parts, which can help to avoid some negative influence on the company and society availably in same degree. During the improving process, enterprises are expected to show new forms of organization and adjust strategic direction, at the same time, the challenges faced required to be solved validly. The main theories, such as Modernism and Symbolic Interpretive, will be the support for case study analysis. Besides, great emphasis should be placed on the controlling and guiding functions triggered by the Stakeholder Theory. This essay will firstly discuss the imaginable issues in the ‘internal’ organization, in order to interpret the occurrence of the Gulf of Mexico oil spill. Following this, it will search out the factors contributing to the Gulf of Mexico oil spill in view of the relationships between the organization and its environment. The essay will combine theories and actual case together, hoping to provide a number of opinions meaningfully for reference.